Basic Information
ID: ALA4730912
Type: Binding
Description: Inhibition of IKKalpha in human HeLa cells assessed as reduction in IL-1 beta-stimulated IKK alpha nuclear translocation at 10 uM pretreated with compound for 4 hrs followed by stimulation with IL-1 beta for 1 hr by immunohistochemical staining/confocal microscopy
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Inhibitor of nuclear factor kappa B kinase alpha subunit(ALA3476)
Document: ALA4725436
Inhibition of IKKalpha in human HeLa cells assessed as reduction in IL-1 beta-stimulated IKK alpha nuclear translocation at 10 uM pretreated with compound for 4 hrs followed by stimulation with IL-1 beta for 1 hr by immunohistochemical staining/confocal microscopy: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4730912
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.39 | 1.32 | 1.32 |