Basic Information
ID: ALA4730913
Type: Binding
Description: Inhibition of IKK alpha nuclear translocation in human HEK-293T cells assessed as reduction in IKK alpha level in nucleus at 15 uM pretreated with compound for 1 hr followed by stimulation with IL-1 beta for 3 hrs by western blot analysis
Format: BAO_0000220
Organism: Homo sapiens
Cell type: HEK-293T
Subcellular Fraction: Nucleus
Target: Inhibitor of nuclear factor kappa B kinase alpha subunit(ALA3476)
Document: ALA4725436
Inhibition of IKK alpha nuclear translocation in human HEK-293T cells assessed as reduction in IKK alpha level in nucleus at 15 uM pretreated with compound for 1 hr followed by stimulation with IL-1 beta for 3 hrs by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4730913
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 358.39 | 1.32 | 1.32 |