Assay Report Card

Basic Information

ID: ALA4730913

Type: Binding

Description: Inhibition of IKK alpha nuclear translocation in human HEK-293T cells assessed as reduction in IKK alpha level in nucleus at 15 uM pretreated with compound for 1 hr followed by stimulation with IL-1 beta for 3 hrs by western blot analysis

Organism: Homo sapiens

Cell type: HEK-293T

Subcellular Fraction: Nucleus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
358.391.321.32