Cytotoxicity against human HepaRG cells infected with HBV assessed as reduction in cell viability at 50 uM treated for 1 hr on day 5 post-infection fo...

Basic Information

ID: ALA4730931

Type: ADME

Description: Cytotoxicity against human HepaRG cells infected with HBV assessed as reduction in cell viability at 50 uM treated for 1 hr on day 5 post-infection followed by removal of media and supplemented with fresh media and further incubated for 3 days then followed by treatment for 1 hr on day 8 post-infection followed by removal of media and supplemented with fresh media and further incubated for 3 days in presence of 10 mM ABT and measured on day 11 post-infection by Celltiter-Glo assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HepaRG

Target:  HepaRG(ALA4630781)

Document:  ALA4725437

Cytotoxicity against human HepaRG cells infected with HBV assessed as reduction in cell viability at 50 uM treated for 1 hr on day 5 post-infection followed by removal of media and supplemented with fresh media and further incubated for 3 days then followed by treatment for 1 hr on day 8 post-infection followed by removal of media and supplemented with fresh media and further incubated for 3 days in presence of 10 mM ABT and measured on day 11 post-infection by Celltiter-Glo assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
353.514.664.66