Potency index, ratio of (1R,3S,4S)-3-amino-4-fluorocyclopentanecarboxylic acid Ki to test compound Ki for binding affinity to pig brain GABA-AT assess...

Basic Information

ID: ALA4731064

Type: Binding

Description: Potency index, ratio of (1R,3S,4S)-3-amino-4-fluorocyclopentanecarboxylic acid Ki to test compound Ki for binding affinity to pig brain GABA-AT assessed as inhibition constant using GABA as substrate in presence of NADP+, alpha-ketoglutarate by SSDH coupled enzyme based UV-Vis spectrophotometry

Format: BAO_0000019

Organism: Sus scrofa

Target:  Gamma-amino-N-butyrate transaminase(ALA2266)

Document:  ALA4725441

Potency index, ratio of (1R,3S,4S)-3-amino-4-fluorocyclopentanecarboxylic acid Ki to test compound Ki for binding affinity to pig brain GABA-AT assessed as inhibition constant using GABA as substrate in presence of NADP+, alpha-ketoglutarate by SSDH coupled enzyme based UV-Vis spectrophotometry: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
145.130.070.07