Assay Report Card

Basic Information

ID: ALA4731266

Type: Functional

Description: In vivo inhibition of GalCer de novo synthesis in PN14 to PN21 days C57BL/6 mouse brain assessed as reduction in [13C] galactose incorporation into GalCer at 10 mg/kg, po bid for 2 days and single dose at day 3 treated 1 hr prior to intraperitoneal injection of [13C] galactose measured after 5 hrs of last dose relative to control

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
528.484.294.29