Basic Information
ID: ALA4731302
Type: Functional
Description: Antagonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as inhibition of THC-induced beta arrestin recruitment after 90 mins by beta-galactosidase based topcount luminescence analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: N-arachidonyl glycine receptor(ALA2384898)
Document: ALA4725451
Antagonist activity at Prolink1-tagged human GPR18 receptor expressed in CHO cells assessed as inhibition of THC-induced beta arrestin recruitment after 90 mins by beta-galactosidase based topcount luminescence analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4731302
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 314.47 | 5.74 | 5.74 |
| 361.53 | 5.33 | 5.33 |
| 339.40 | 0.89 | 0.89 |
| 369.43 | 0.90 | 0.90 |
| 373.84 | 1.54 | 1.54 |
| 399.45 | 0.90 | 0.90 |
| 378.44 | 1.37 | 1.37 |
| 434.54 | 3.11 | 3.11 |
| 359.82 | 1.50 | 1.50 |
| 314.47 | 5.85 | 5.85 |
| 263.30 | -0.34 | -0.34 |
| 305.38 | 0.83 | 0.83 |
| 378.51 | 3.69 | 3.69 |
| 293.33 | -0.71 | -0.71 |
| 291.36 | 0.44 | 0.44 |
| 392.46 | 1.76 | 1.76 |
| 364.41 | 0.98 | 0.98 |
| 313.32 | 0.29 | 0.29 |
| 334.42 | -0.01 | -0.01 |