Basic Information
ID: ALA4731320
Type: ADME
Description: Binding affinity to N-terminal 6His-SUMO-tagged human full length FKBP12 expressed in Escherichia coli BL21 (DE3) cells assessed as change in melting temperature at 40 uM by differential scanning colorimetric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4731320
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 538.69 | 4.85 | 4.85 |
| 646.74 | 5.77 | 5.77 |
| 550.70 | 5.86 | 5.86 |
| 552.71 | 6.09 | 6.09 |
| 496.65 | 5.32 | 5.32 |
| 536.67 | 4.63 | 4.63 |
| 646.74 | 5.77 | 5.77 |
| 494.63 | 4.47 | 4.47 |
| 367.43 | 2.49 | 2.49 |
| 550.70 | 5.86 | 5.86 |
| 550.70 | 5.86 | 5.86 |
| 539.67 | 5.28 | 5.28 |
| 556.66 | 5.74 | 5.74 |
| 369.45 | 2.71 | 2.71 |
| 367.43 | 2.49 | 2.49 |
| 555.67 | 5.20 | 5.20 |
| 537.65 | 5.06 | 5.06 |
| 610.70 | 4.09 | 4.09 |
| 586.69 | 5.75 | 5.75 |