Basic Information
ID: ALA4731348
Type: Binding
Description: Inhibition of recombinant human His-tagged KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and measured after 15 mins by ADP-Glo kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4731348
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 556.61 | 4.17 | 4.17 |
| 556.61 | 4.17 | 4.17 |
| 542.58 | 3.32 | 3.32 |
| 505.59 | 3.85 | 3.85 |
| 529.66 | 2.21 | 2.21 |
| 529.66 | 2.59 | 2.59 |