Basic Information
ID: ALA4731421
Type: Binding
Description: Inhibition of human PI3K p110alpha/p85alpha at 10 uM using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in presence of 10 uM ATP by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4731421
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.98 | 2.98 |
| 349.39 | 3.11 | 3.11 |
| 391.43 | 3.31 | 3.31 |
| 505.56 | 3.31 | 3.31 |
| 316.36 | 3.01 | 3.01 |
| 405.46 | 3.70 | 3.70 |
| 379.42 | 2.60 | 2.60 |
| 462.54 | 3.41 | 3.41 |
| 511.59 | 3.37 | 3.37 |
| 393.45 | 2.65 | 2.65 |
| 317.35 | 0.58 | 0.58 |
| 504.57 | 3.91 | 3.91 |
| 470.52 | 1.28 | 1.28 |
| 335.36 | 2.83 | 2.83 |
| 428.47 | 1.76 | 1.76 |
| 406.45 | 2.47 | 2.47 |
| 421.46 | 3.29 | 3.29 |
| 287.32 | 1.22 | 1.22 |
| 385.45 | 1.86 | 1.86 |
| 379.42 | 2.60 | 2.60 |
| 348.41 | 3.41 | 3.41 |
| 463.52 | 2.80 | 2.80 |
| 540.55 | 4.19 | 4.19 |
| 522.56 | 4.05 | 4.05 |
| 308.34 | 2.23 | 2.23 |
| 406.45 | 3.07 | 3.07 |
| 468.56 | 3.47 | 3.47 |
| 442.50 | 2.48 | 2.48 |
| 506.55 | 2.70 | 2.70 |
| 378.43 | 3.39 | 3.39 |
| 427.49 | 1.38 | 1.38 |