Basic Information
ID: ALA4731576
Type: Binding
Description: Non-competitive inhibition of full-length human N-terminal FLAG-tagged PRMT5/full length N-terminal His6-tagged MEP50 (unknown origin) expressed in baculovirus infected Sf9 insect cells assessed as reduction of S-adenosyl-L-homocysteine formation using human recombinant histone H2A (1 to 130 residues) and varying concentrations of S-adenosyl-L-methionine as substrate after 80 mins by rapidfire mass spectrometry analysis
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4731576
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.47 | -0.15 | -0.15 |
| 402.50 | 0.19 | 0.19 |