Basic Information
ID: ALA4731740
Type: Binding
Description: Activation of N-terminal His-tagged human SIRT6 (1 to 355 residues) expressed in Escherichia coli M15(pREP4) assessed as increase in deacetylation activity using acetyl-H3K9 peptide as substrate incubated for 2 hrs in presence of NAD+ by mass spectrometric analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent protein deacetylase sirtuin-6(ALA2163182)
Document: ALA4725480
Activation of N-terminal His-tagged human SIRT6 (1 to 355 residues) expressed in Escherichia coli M15(pREP4) assessed as increase in deacetylation activity using acetyl-H3K9 peptide as substrate incubated for 2 hrs in presence of NAD+ by mass spectrometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4731740
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.47 | 4.63 | 4.63 |