Basic Information
ID: ALA4731742
Type: ADME
Description: Inhibition of N-terminal His-tagged human recombinant SIRT2 (55 to 356 residues) expressed in Escherichia coli Rossetta2 cells assessed as decrease in substrate deacetylation activity using QPK(acetyl-K) as substrate at 250 to 1000 uM incubated for 30 mins by fluorescence based analysis
Format: BAO_0000219
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 2(ALA4462)
Document: ALA4725480
Inhibition of N-terminal His-tagged human recombinant SIRT2 (55 to 356 residues) expressed in Escherichia coli Rossetta2 cells assessed as decrease in substrate deacetylation activity using QPK(acetyl-K) as substrate at 250 to 1000 uM incubated for 30 mins by fluorescence based analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4731742
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.47 | 4.63 | 4.63 |