Basic Information
ID: ALA4731743
Type: ADME
Description: Inhibition of N-terminal His-tagged human recombinant SIRT3 (118 to 399 residues) expressed in Escherichia coli assessed as decrease in substrate deacetylation using QPK(acetyl-K) as substrate at 250 to 1000 uM incubated for 30 mins by fluorescence based analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: NAD-dependent deacetylase sirtuin 3(ALA4461)
Document: ALA4725480
Inhibition of N-terminal His-tagged human recombinant SIRT3 (118 to 399 residues) expressed in Escherichia coli assessed as decrease in substrate deacetylation using QPK(acetyl-K) as substrate at 250 to 1000 uM incubated for 30 mins by fluorescence based analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4731743
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.47 | 4.63 | 4.63 |