Basic Information
ID: ALA4731745
Type: Binding
Description: Activation of His-tagged N-terminal truncated human SIRT6 (13 to 355 residues) expressed in Escherichia coli BL21 (DE3) codon+ cells assessed as increase in deacetylation activity using acetyl-H3K9 peptide as substrate incubated for 2 hrs in presence of NAD+ by mass spectrometric analysis relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: NAD-dependent protein deacetylase sirtuin-6(ALA2163182)
Document: ALA4725480
Activation of His-tagged N-terminal truncated human SIRT6 (13 to 355 residues) expressed in Escherichia coli BL21 (DE3) codon+ cells assessed as increase in deacetylation activity using acetyl-H3K9 peptide as substrate incubated for 2 hrs in presence of NAD+ by mass spectrometric analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4731745
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 411.47 | 4.63 | 4.63 |