Assay Report Card

Basic Information

ID: ALA4731777

Type: Binding

Description: Protac activity at CRBN/SIRT2 in human MCF7 cells assessed as SIRT2 degradation at 5 uM preincubated with proteasome inhibitior MG132 for 2 hrs followed by compound addition measured after 16 hrs by immunoblot analysis

Organism: Homo sapiens

Cell type: MCF7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
951.246.876.87