Basic Information
ID: ALA4731778
Type: Binding
Description: Protac activity at CRBN/SIRT2 in human HEK293T cells stably expressing flag-tagged K-Ras4a assessed as inhibition of SIRT2 defatty-acylation at 10 uM incubated for 42 hrs followed by Alkyne-14 addition and measured after 6 hrs by immunoprecipitation based assay
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4731778
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.87 | 8.71 | 8.71 |