Basic Information
ID: ALA4731780
Type: Binding
Description: Protac activity at CRBN/SIRT2 in human MCF7 cells assessed as inhibition of SIRT2 deacetylation by measuring increase in acetylated-alpha tubulin level at 10 uM measured after 12 hrs by DAPI staining based immunofluorescence microscopic analysis
Organism: Homo sapiens
Cell type: MCF7
Activity Charts
Bioactivity
Activity Types for Assay ALA4731780
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 581.87 | 8.71 | 8.71 |
| 951.24 | 6.87 | 6.87 |