ID: ALA4731781
Type: Binding
Description: Protac activity at CRBN/SIRT2 in human HEK293T cells stably expressing flag-tagged K-Ras4a assessed as inhibition of SIRT2 defatty-acylation at 1 uM incubated for 42 hrs followed by Alkyne-14 addition and measured after 6 hrs by immunoprecipitation based assay
Organism: Homo sapiens
Cell type: HEK-293T
Bioactivity
Activity Types for Assay ALA4731781
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
951.24 | 6.87 | 6.87 |