Assay Report Card

Basic Information

ID: ALA4731781

Type: Binding

Description: Protac activity at CRBN/SIRT2 in human HEK293T cells stably expressing flag-tagged K-Ras4a assessed as inhibition of SIRT2 defatty-acylation at 1 uM incubated for 42 hrs followed by Alkyne-14 addition and measured after 6 hrs by immunoprecipitation based assay

Organism: Homo sapiens

Cell type: HEK-293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
951.246.876.87