Assay Report Card

Basic Information

ID: ALA4731782

Type: Binding

Description: Protac activity at CRBN/SIRT2 in human HEK293T cells stably expressing flag-tagged K-Ras4a-G12V assessed as inhibition of SIRT2 defatty-acylation at 1 uM incubated for 48 hrs by immunoblot analysis

Organism: Homo sapiens

Cell type: HEK-293T

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
951.246.876.87