Basic Information
ID: ALA4731783
Type: Binding
Description: Protac activity at CRBN/SIRT1 in human HEK293T cells stably expressing flag-tagged K-Ras4a-G12V assessed as inhibition of SIRT2 defatty-acylation at 1 uM incubated for 48 hrs by immunoblot analysis
Organism: Homo sapiens
Cell type: HEK-293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4731783
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 951.24 | 6.87 | 6.87 |