Assay Report Card

Basic Information

ID: ALA4731835

Type: Toxicity

Description: Therapeutic index, ratio of TC50 for human GHOST CXCR4 cells assessed as reduction in cell viability incubated for 4 hrs by XTT assay to EC50 for HIV1 3B reverse transcriptase infected in human GHOST CXCR4 cells assessed as reduction in viral replication incubated for 60 to 90 mins in presence of DTT and TTP by liquid scintillation counter

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
406.675.375.37
980.272.252.25
751.032.502.50