Basic Information
ID: ALA4731848
Type: Binding
Description: Inhibition of recombinant human His-tagged KIF18A (1 to 467 residues) expressed in baculovirus expression system assessed as inhibition of microtubule-stimulated ATPase activity preincubated for 15 mins followed by ATP addition and measured after 15 mins by ADP-Glo kinase assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4731848
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 532.67 | 2.33 | 2.33 |
| 515.64 | 3.08 | 3.08 |
| 549.64 | 3.68 | 3.68 |
| 544.68 | 2.46 | 2.46 |
| 540.69 | 3.14 | 3.14 |
| 563.67 | 4.44 | 4.44 |