Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysis

Basic Information

ID: ALA4732438

Type: Binding

Description: Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: A2058

Target: Unchecked(ALA612545)

Document: ALA4732024

Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4732438

IC50

Total(9)

Parent Molecular Weight	ALogP	Polar Surface Area
418.45	2.04	2.04
437.43	1.52	1.52
419.44	1.44	1.44
375.46	0.56	0.56
436.44	2.13	2.13
436.44	2.13	2.13
374.47	1.17	1.17
369.43	0.50	0.50
375.46	0.56	0.56

Parent Molecular Weight

ALogP

Polar Surface Area

418.45

2.04

437.43

1.52

419.44

1.44

375.46

0.56

436.44

2.13

436.44

2.13

374.47

1.17

369.43

0.50

375.46

0.56

Inhibition of mTORC2 in human A2058 cells assessed as reduction in PKB phosphorylation at S473 residue incubated for 1 hr by Western blot analysis

Basic Information

Activity Charts

Compound Summary