Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assay

Basic Information

ID: ALA4732595

Type: Functional

Description: Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target:  G-protein coupled bile acid receptor 1(ALA5409)

Document:  ALA4732028

Agonist activity at recombinant human TGR5 expressed in CHO cells assessed as increase in cAMP accumulation after 30 mins by TR-FRET assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
483.724.434.43
430.634.944.94
444.665.595.59
507.764.834.83
569.781.601.60
583.811.941.94
406.615.135.13
876.10-2.24-2.24