Basic Information
ID: ALA4733681
Type: Binding
Description: Inhibition of human 17-beta-HSD10 expressed in HEK293 cells assessed as reduction in oxidation of [14C]-estradiol to [14C]-estrone incubated for 40 hrs by thin layer chromatography
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Unchecked(ALA612545)
Document: ALA4732072
Inhibition of human 17-beta-HSD10 expressed in HEK293 cells assessed as reduction in oxidation of [14C]-estradiol to [14C]-estrone incubated for 40 hrs by thin layer chromatography: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4733681
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 508.75 | 5.16 | 5.16 |
| 534.74 | 4.99 | 4.99 |
| 605.81 | 6.04 | 6.04 |
| 529.77 | 5.70 | 5.70 |
| 596.81 | 6.02 | 6.02 |
| 568.80 | 6.45 | 6.45 |
| 522.77 | 5.46 | 5.46 |
| 520.76 | 5.40 | 5.40 |
| 630.92 | 4.59 | 4.59 |
| 509.76 | 3.14 | 3.14 |
| 602.78 | 5.97 | 5.97 |
| 522.77 | 5.46 | 5.46 |
| 576.74 | 6.17 | 6.17 |
| 578.76 | 5.97 | 5.97 |
| 517.71 | 4.66 | 4.66 |