Basic Information
ID: ALA4733682
Type: Binding
Description: Potency index, ratio of (3R,5S,8R,9S,10S,13S,14S)-3-hydroxy-3-((4-(3-methoxybenzyl)piperazin-1-yl)methyl)-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one IC50 to compound IC50 for inhibition of human 17-beta-HSD10 expressed in HEK-293 cells
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Unchecked(ALA612545)
Document: ALA4732072
Potency index, ratio of (3R,5S,8R,9S,10S,13S,14S)-3-hydroxy-3-((4-(3-methoxybenzyl)piperazin-1-yl)methyl)-10,13-dimethyltetradecahydro-1H-cyclopenta[a]phenanthren-17(2H)-one IC50 to compound IC50 for inhibition of human 17-beta-HSD10 expressed in HEK-293 cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4733682
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 534.74 | 4.99 | 4.99 |
| 605.81 | 6.04 | 6.04 |
| 529.77 | 5.70 | 5.70 |
| 596.81 | 6.02 | 6.02 |
| 568.80 | 6.45 | 6.45 |
| 522.77 | 5.46 | 5.46 |
| 520.76 | 5.40 | 5.40 |
| 630.92 | 4.59 | 4.59 |
| 509.76 | 3.14 | 3.14 |
| 602.78 | 5.97 | 5.97 |
| 522.77 | 5.46 | 5.46 |
| 576.74 | 6.17 | 6.17 |
| 578.76 | 5.97 | 5.97 |
| 517.71 | 4.66 | 4.66 |