Basic Information
ID: ALA4733695
Type: Binding
Description: Protac activity at CRBN/GSK3beta in rat PC12 cells assessed as GSK3beta degradation by measuring GSK3beta protein level at 10 uM after 10 hrs by Western blotting analysis (Rvb = 95.3 to 100.6 %)
Organism: Rattus norvegicus
Cell type: PC-12
Activity Charts
Bioactivity
Activity Types for Assay ALA4733695
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 273.25 | -0.33 | -0.33 |
| 783.87 | 3.90 | 3.90 |
| 730.84 | 4.89 | 4.89 |
| 758.90 | 5.67 | 5.67 |
| 628.67 | 1.86 | 1.86 |
| 656.68 | 1.76 | 1.76 |
| 702.79 | 4.11 | 4.11 |
| 642.69 | 2.12 | 2.12 |
| 750.79 | 1.82 | 1.82 |
| 626.69 | 2.88 | 2.88 |
| 706.73 | 1.81 | 1.81 |
| 642.65 | 1.50 | 1.50 |
| 304.33 | 1.36 | 1.36 |
| 640.68 | 2.53 | 2.53 |
| 794.84 | 1.84 | 1.84 |
| 787.81 | 1.60 | 1.60 |
| 831.87 | 1.61 | 1.61 |