Basic Information
ID: ALA4733702
Type: Binding
Description: Protac activity at CRBN/GSK3beta in rat PC12 cells assessed as GSK3beta degradation by measuring GSK3beta protein level at 8.3 uM preincubated for 2 hrs with GSK3beta inhibitor, G1 followed by compound addition and measured after 8 hrs by Western blotting analysis (Rvb = 100 %)
Organism: Rattus norvegicus
Cell type: PC-12
Activity Charts
Bioactivity
Activity Types for Assay ALA4733702
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 783.87 | 3.90 | 3.90 |