Basic Information
ID: ALA4733842
Type: Binding
Description: Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in rhIGF1-stimulated AKT phosphorylation at Ser473 treated for 1 hr followed by incubation with IGF1 for 10 mins by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: U-87 MG
Target: PI3-kinase p110-alpha subunit(ALA4005)
Document: ALA4732078
Inhibition of PI3Kalpha in human U87MG cells assessed as reduction in rhIGF1-stimulated AKT phosphorylation at Ser473 treated for 1 hr followed by incubation with IGF1 for 10 mins by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4733842
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 598.61 | 1.90 | 1.90 |