Basic Information
ID: ALA4733889
Type: Functional
Description: In vivo inhibition of PI3Kalpha in BALB/cA nude mouse xenografted with human SK-OV-3 cells assessed as reduction in AKT phosphorylation at Ser473 residue in tumor at 5 mg/kg, po measured after 4 to 8 hrs by Western blot analysis
Format: BAO_0000218
Organism: Mus musculus
Strain: BALB/cA
Target: Unchecked(ALA612545)
Document: ALA4732078
In vivo inhibition of PI3Kalpha in BALB/cA nude mouse xenografted with human SK-OV-3 cells assessed as reduction in AKT phosphorylation at Ser473 residue in tumor at 5 mg/kg, po measured after 4 to 8 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4733889
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 598.61 | 1.90 | 1.90 |