Basic Information
ID: ALA4733963
Type: Binding
Description: Inhibition of NAE (unknown origin)-mediated neddylation assessed as suppression of cullin1-Nedd8 adduct formation preincubated for 10 mins followed by ATP addition and measured after 30 mins by immunoblot analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4733963
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 610.67 | 6.32 | 6.32 |
| 443.53 | 2.06 | 2.06 |
| 582.67 | 5.78 | 5.78 |
| 612.52 | 6.61 | 6.61 |
| 612.52 | 6.61 | 6.61 |