Basic Information
ID: ALA4734035
Type: Functional
Description: Antagonist activity at adrenergic alpha 2 receptor in human brain membrane assessed as inhibition of UK14304-induced stimulation of [35S]GTPgammaS binding by liquid scintillation spectroscopy (Rvb = 1.77 +/- 0.16 uM)
Organism: Homo sapiens
Tissue: Brain
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA4734035
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 234.25 | 0.80 | 0.80 |
| 381.31 | 1.76 | 1.76 |
| 424.38 | 2.39 | 2.39 |
| 423.39 | 2.99 | 2.99 |
| 461.40 | 3.38 | 3.38 |
| 424.38 | 2.39 | 2.39 |
| 425.37 | 1.78 | 1.78 |
| 462.39 | 2.77 | 2.77 |
| 382.30 | 1.35 | 1.35 |