Basic Information
ID: ALA4734042
Type: Binding
Description: Inhibition of recombinant human CDC7/Dbf4 expressed in baculovirus infected Sf9 insect cells assessed as inhibition of fluorescein labelled substrate phosphorylation in presence of ATP measured after 60 mins by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase)(ALA2111377)
Document: ALA4732086
Inhibition of recombinant human CDC7/Dbf4 expressed in baculovirus infected Sf9 insect cells assessed as inhibition of fluorescein labelled substrate phosphorylation in presence of ATP measured after 60 mins by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4734042
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 226.24 | 1.88 | 1.88 |
| 242.31 | 2.65 | 2.65 |
| 315.31 | 2.19 | 2.19 |
| 276.75 | 3.25 | 3.25 |
| 304.76 | 2.93 | 2.93 |
| 321.20 | 3.36 | 3.36 |
| 259.70 | 2.62 | 2.62 |
| 276.75 | 3.30 | 3.30 |
| 321.20 | 3.41 | 3.41 |
| 241.32 | 3.25 | 3.25 |
| 267.32 | 2.52 | 2.52 |
| 272.33 | 2.14 | 2.14 |
| 310.30 | 3.66 | 3.66 |
| 368.20 | 3.25 | 3.25 |
| 368.20 | 3.25 | 3.25 |
| 320.22 | 4.01 | 4.01 |
| 272.33 | 2.65 | 2.65 |
| 258.31 | 2.51 | 2.51 |
| 368.20 | 3.25 | 3.25 |
| 274.32 | 2.83 | 2.83 |
| 260.68 | 2.59 | 2.59 |
| 276.75 | 3.30 | 3.30 |
| 290.78 | 3.34 | 3.34 |
| 260.30 | 2.78 | 2.78 |
| 307.18 | 3.27 | 3.27 |
| 310.30 | 3.66 | 3.66 |
| 321.20 | 3.41 | 3.41 |
| 288.40 | 3.37 | 3.37 |
| 349.21 | 3.09 | 3.09 |
| 290.78 | 3.34 | 3.34 |
| 267.32 | 2.52 | 2.52 |
| 310.30 | 3.66 | 3.66 |
| 287.30 | 2.55 | 2.55 |
| 305.13 | 2.69 | 2.69 |
| 290.78 | 3.34 | 3.34 |
| 299.36 | 2.60 | 2.60 |
| 287.30 | 2.55 | 2.55 |