Basic Information
ID: ALA4734085
Type: Binding
Description: Inhibition of human CDC7 in human SH-SY5Y cells assessed as prevention of ethacrynic acid-induced cell death preincubated for 1 hr followed by incubation with ethacrynic acid for 24 hrs measured at 10 uM by MTT assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: Cell division cycle 7-related protein kinase(ALA5443)
Document: ALA4732086
Inhibition of human CDC7 in human SH-SY5Y cells assessed as prevention of ethacrynic acid-induced cell death preincubated for 1 hr followed by incubation with ethacrynic acid for 24 hrs measured at 10 uM by MTT assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4734085
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 242.31 | 2.65 | 2.65 |
| 276.75 | 3.25 | 3.25 |
| 321.20 | 3.36 | 3.36 |
| 276.75 | 3.30 | 3.30 |
| 241.32 | 3.25 | 3.25 |
| 310.30 | 3.66 | 3.66 |
| 368.20 | 3.25 | 3.25 |
| 368.20 | 3.25 | 3.25 |
| 272.33 | 2.65 | 2.65 |
| 368.20 | 3.25 | 3.25 |
| 274.32 | 2.83 | 2.83 |
| 260.68 | 2.59 | 2.59 |
| 276.75 | 3.30 | 3.30 |
| 290.78 | 3.34 | 3.34 |
| 260.30 | 2.78 | 2.78 |
| 310.30 | 3.66 | 3.66 |
| 321.20 | 3.41 | 3.41 |
| 288.40 | 3.37 | 3.37 |
| 290.78 | 3.34 | 3.34 |
| 310.30 | 3.66 | 3.66 |
| 305.13 | 2.69 | 2.69 |
| 290.78 | 3.34 | 3.34 |
| 287.30 | 2.55 | 2.55 |