Basic Information
ID: ALA4734206
Type: Binding
Description: Antagonist activity at sigma1 receptor in rat PC12 cells assessed as reduction in opipramol activity by measuring increase in Ca2+-influx at 10 nM measured after 30 mins in presence of KCl by Fura2AM dye based fluorescence microscopic analysis relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: PC-12
Target: Sigma opioid receptor(ALA3602)
Document: ALA4732089
Antagonist activity at sigma1 receptor in rat PC12 cells assessed as reduction in opipramol activity by measuring increase in Ca2+-influx at 10 nM measured after 30 mins in presence of KCl by Fura2AM dye based fluorescence microscopic analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4734206
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 257.42 | 4.45 | 4.45 |
| 293.45 | 5.14 | 5.14 |
| 293.45 | 5.14 | 5.14 |