Basic Information
ID: ALA4734505
Type: Binding
Description: Inhibition of Leishmania major DHFR in promastigote stage Leishmania major using dihydrofolic acid as substrate in presence of NADPH measured after 5 days by spectrophotometric method
Organism: Leishmania major
Activity Charts
Bioactivity
Activity Types for Assay ALA4734505
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 290.32 | 1.26 | 1.26 |
| 480.48 | 2.00 | 2.00 |
| 463.45 | 0.06 | 0.06 |
| 568.59 | 1.79 | 1.79 |
| 514.92 | 2.65 | 2.65 |
| 494.50 | 2.31 | 2.31 |
| 447.49 | 1.24 | 1.24 |
| 510.50 | 2.01 | 2.01 |
| 625.69 | 3.65 | 3.65 |
| 538.61 | 2.58 | 2.58 |
| 520.55 | 1.92 | 1.92 |
| 481.51 | 1.44 | 1.44 |
| 586.65 | 3.17 | 3.17 |
| 525.47 | 1.91 | 1.91 |