Basic Information
ID: ALA4734520
Type: Binding
Description: Inhibition of ABCB1 in human resistant COLO 320 cells assessed as multidrug resistance reversing activity by measuring fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry
Format: BAO_0000221
Organism: Homo sapiens
Cell type: COLO 320
Target: P-glycoprotein 1(ALA4302)
Document: ALA4732098
Inhibition of ABCB1 in human resistant COLO 320 cells assessed as multidrug resistance reversing activity by measuring fluorescence activity ratio at 2 uM preincubated for 10 mins followed by rhodamine-123 addition and measured after 20 mins by flow cytometry: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4734520
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 354.45 | 3.04 | 3.04 |
| 354.45 | 3.04 | 3.04 |
| 537.50 | 5.52 | 5.52 |
| 394.52 | 3.70 | 3.70 |
| 537.50 | 5.52 | 5.52 |
| 474.60 | 4.57 | 4.57 |
| 479.02 | 5.22 | 5.22 |
| 548.68 | 5.80 | 5.80 |
| 458.60 | 4.87 | 4.87 |
| 474.60 | 4.57 | 4.57 |
| 458.60 | 4.87 | 4.87 |
| 489.57 | 4.47 | 4.47 |
| 489.57 | 4.47 | 4.47 |
| 445.56 | 3.96 | 3.96 |
| 396.53 | 3.93 | 3.93 |
| 488.63 | 4.77 | 4.77 |
| 382.50 | 3.54 | 3.54 |
| 523.47 | 5.33 | 5.33 |
| 474.60 | 4.57 | 4.57 |
| 479.02 | 5.22 | 5.22 |
| 479.02 | 5.22 | 5.22 |
| 488.63 | 4.77 | 4.77 |
| 382.50 | 3.54 | 3.54 |
| 458.60 | 4.87 | 4.87 |
| 504.63 | 4.58 | 4.58 |
| 523.47 | 5.33 | 5.33 |
| 396.53 | 3.93 | 3.93 |
| 412.53 | 2.90 | 2.90 |