Basic Information
ID: ALA4735020
Type: Binding
Description: Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells at 0.1 uM preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-glo luminescence assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Acetyl-CoA carboxylase 1(ALA3351)
Document: ALA4732112
Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells at 0.1 uM preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-glo luminescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4735020
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.47 | 3.15 | 3.15 |
| 452.94 | 4.48 | 4.48 |
| 503.60 | 3.66 | 3.66 |
| 508.62 | 5.80 | 5.80 |
| 529.04 | 6.15 | 6.15 |
| 462.55 | 4.23 | 4.23 |
| 554.65 | 5.51 | 5.51 |
| 448.52 | 3.84 | 3.84 |
| 509.61 | 5.08 | 5.08 |
| 537.66 | 5.56 | 5.56 |
| 529.04 | 6.15 | 6.15 |
| 516.65 | 3.58 | 3.58 |
| 495.58 | 4.89 | 4.89 |
| 502.62 | 3.24 | 3.24 |
| 573.49 | 6.26 | 6.26 |
| 476.58 | 4.61 | 4.61 |
| 495.58 | 4.89 | 4.89 |
| 508.62 | 5.80 | 5.80 |
| 524.62 | 5.50 | 5.50 |
| 494.60 | 5.49 | 5.49 |
| 432.52 | 4.13 | 4.13 |
| 512.59 | 5.63 | 5.63 |