Basic Information
ID: ALA4735021
Type: Binding
Description: Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-glo luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Acetyl-CoA carboxylase 1(ALA3351)
Document: ALA4732112
Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells preincubated for 15 mins followed by substrate addition and measured after 60 mins by ADP-glo luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4735021
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.47 | 3.15 | 3.15 |
| 569.64 | 3.95 | 3.95 |
| 452.94 | 4.48 | 4.48 |
| 503.60 | 3.66 | 3.66 |
| 508.62 | 5.80 | 5.80 |
| 529.04 | 6.15 | 6.15 |
| 462.55 | 4.23 | 4.23 |
| 554.65 | 5.51 | 5.51 |
| 448.52 | 3.84 | 3.84 |
| 509.61 | 5.08 | 5.08 |
| 537.66 | 5.56 | 5.56 |
| 529.04 | 6.15 | 6.15 |
| 516.65 | 3.58 | 3.58 |
| 495.58 | 4.89 | 4.89 |
| 502.62 | 3.24 | 3.24 |
| 573.49 | 6.26 | 6.26 |
| 476.58 | 4.61 | 4.61 |
| 495.58 | 4.89 | 4.89 |
| 508.62 | 5.80 | 5.80 |
| 524.62 | 5.50 | 5.50 |
| 494.60 | 5.49 | 5.49 |
| 432.52 | 4.13 | 4.13 |
| 512.59 | 5.63 | 5.63 |