Assay Report Card

Basic Information

ID: ALA4735221

Type: ADME

Description: Effect on activated cytotoxic T cell population in mouse B16/F10 cells implanted humanized PD-1 C57BL/6J mouse assessed as CD3-positive cell population at 100 mg/kg, ig administered once daily via gavage for 14 days measured post-last dose by immunostaining based flow cytometry (Rvb = 20.3 %)

Organism: Mus musculus

Strain: C57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
434.495.285.28