Assay Report Card

Basic Information

ID: ALA4735328

Type: Functional

Description: Immunostimulatory activity in mouse B16-F10 cells implanted humanized PD-1 C57BL/6J mouse assessed as increase in activation of tumor-microenvironment by measuring PD-L1 expression in tumor at 100 mg/kg, ig administered once daily via gavage for 14 days measured post-last dose by immunostaining based flow cytometry (Rvb = 23.8%)

Organism: Mus musculus

Strain: C57BL/6J

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
434.495.285.28