Basic Information
ID: ALA4735343
Type: Binding
Description: Inhibition of human EZH2 (2 to 746 residues) expressed in baculovirus infected insect cells using histone H3 as substrate preincubated for 10 mins followed by S-adenosyl-L-[methyl-3H]methionine and measured after 60 mins by radiometric HotSpot assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4735343
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.46 | 3.54 | 3.54 |
| 511.67 | 4.84 | 4.84 |