Basic Information
ID: ALA4735444
Type: Functional
Description: Antiproliferative activity against human A549 cells harboring KRAS G12S mutant assessed as growth inhibition at 0.1 uM measured after 72 hrs by SRB assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A549
Target: A549(ALA392)
Document: ALA4732119
Antiproliferative activity against human A549 cells harboring KRAS G12S mutant assessed as growth inhibition at 0.1 uM measured after 72 hrs by SRB assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4735444
GI
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.84 | 3.77 | 3.77 |
| 560.61 | 4.48 | 4.48 |
| 552.61 | 4.71 | 4.71 |
| 538.61 | 4.44 | 4.44 |
| 540.60 | 4.87 | 4.87 |
| 560.61 | 4.64 | 4.64 |
| 543.60 | 3.74 | 3.74 |
| 540.60 | 4.87 | 4.87 |
| 542.62 | 4.34 | 4.34 |
| 536.64 | 5.04 | 5.04 |
| 558.59 | 5.01 | 5.01 |
| 554.63 | 4.18 | 4.18 |
| 610.61 | 5.27 | 5.27 |
| 552.61 | 5.01 | 5.01 |
| 597.70 | 4.80 | 4.80 |