Basic Information
ID: ALA4735573
Type: Binding
Description: Inhibition of recombinant human MMP8 (99 to 269 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system as substrate incubated for 15 mins followed by substrate addition and measured after 2 to 4 hrs by fluorescence based assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Matrix metalloproteinase 8(ALA4588)
Document: ALA4732123
Inhibition of recombinant human MMP8 (99 to 269 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system as substrate incubated for 15 mins followed by substrate addition and measured after 2 to 4 hrs by fluorescence based assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4735573
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 362.43 | 6.09 | 6.09 |
| 398.49 | 6.16 | 6.16 |
| 352.39 | 5.68 | 5.68 |
| 376.46 | 6.40 | 6.40 |
| 348.47 | 5.62 | 5.62 |
| 286.33 | 3.93 | 3.93 |
| 380.45 | 6.30 | 6.30 |
| 452.51 | 6.12 | 6.12 |
| 392.46 | 6.10 | 6.10 |
| 392.46 | 6.10 | 6.10 |
| 368.46 | 6.15 | 6.15 |
| 376.46 | 6.10 | 6.10 |
| 380.42 | 6.23 | 6.23 |
| 382.42 | 5.69 | 5.69 |
| 405.50 | 6.16 | 6.16 |
| 386.45 | 6.29 | 6.29 |
| 370.38 | 5.82 | 5.82 |
| 342.44 | 5.56 | 5.56 |
| 292.36 | 3.99 | 3.99 |
| 377.45 | 5.67 | 5.67 |