Basic Information
ID: ALA4735963
Type: Binding
Description: Inhibition of amyloid beta (1 to 42) (unknown origin) assessed as reduction in peptide aggregation at 2 uM measured after 24 hrs by thioflavin-T fluorescence assay relative to control
Format: BAO_0000357
Organism: Homo sapiens
Target: Amyloid-beta A4 protein(ALA2487)
Document: ALA4732135
Inhibition of amyloid beta (1 to 42) (unknown origin) assessed as reduction in peptide aggregation at 2 uM measured after 24 hrs by thioflavin-T fluorescence assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4735963
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 400.52 | 0.23 | 0.23 |
| 516.56 | 1.84 | 1.84 |
| 438.57 | 0.86 | 0.86 |
| 463.58 | 0.40 | 0.40 |
| 443.55 | -0.91 | -0.91 |
| 412.53 | 0.47 | 0.47 |
| 414.55 | 0.62 | 0.62 |
| 457.57 | -0.52 | -0.52 |
| 414.55 | 0.62 | 0.62 |
| 386.49 | -0.02 | -0.02 |
| 458.56 | 0.08 | 0.08 |
| 370.49 | 0.16 | 0.16 |
| 448.56 | 1.34 | 1.34 |
| 449.55 | 0.21 | 0.21 |
| 483.01 | 1.47 | 1.47 |
| 412.53 | 0.37 | 0.37 |
| 444.53 | -0.31 | -0.31 |
| 462.59 | 1.08 | 1.08 |
| 493.56 | 0.73 | 0.73 |
| 504.67 | 2.19 | 2.19 |
| 452.60 | 1.25 | 1.25 |
| 414.55 | 0.57 | 0.57 |
| 414.55 | 0.57 | 0.57 |
| 462.59 | 1.13 | 1.13 |
| 372.47 | -0.41 | -0.41 |
| 412.53 | 0.52 | 0.52 |
| 466.55 | 0.96 | 0.96 |
| 424.54 | 0.63 | 0.63 |
| 504.67 | 2.11 | 2.11 |
| 372.47 | -0.26 | -0.26 |
| 428.57 | 1.01 | 1.01 |
| 496.61 | 1.40 | 1.40 |
| 400.52 | 0.23 | 0.23 |
| 498.62 | 1.97 | 1.97 |
| 400.52 | 0.23 | 0.23 |
| 398.50 | -0.02 | -0.02 |
| 316.36 | -1.82 | -1.82 |
| 400.52 | 0.33 | 0.33 |
| 524.66 | 2.48 | 2.48 |