Basic Information
ID: ALA4736565
Type: Binding
Description: Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 mins by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Transitional endoplasmic reticulum ATPase(ALA1075145)
Document: ALA4732155
Inhibition of p97 in human HeLa cells assessed as reduction in proteasomal turnover of p97-dependent reporter substrate UbG76V-GFP incubated for 120 mins by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4736565
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 195.17 | 1.65 | 1.65 |
| 342.37 | 2.52 | 2.52 |
| 358.83 | 2.79 | 2.79 |
| 299.28 | 3.16 | 3.16 |
| 193.16 | 1.66 | 1.66 |
| 209.20 | 1.95 | 1.95 |
| 192.17 | 1.51 | 1.51 |
| 366.42 | 5.16 | 5.16 |
| 317.40 | 3.98 | 3.98 |
| 267.34 | 2.83 | 2.83 |
| 239.10 | 2.63 | 2.63 |
| 630.45 | 5.58 | 5.58 |
| 246.03 | 2.84 | 2.84 |
| 331.42 | 4.44 | 4.44 |
| 194.15 | 1.84 | 1.84 |
| 343.82 | 3.43 | 3.43 |
| 425.49 | 4.63 | 4.63 |
| 343.43 | 4.50 | 4.50 |
| 451.53 | 5.15 | 5.15 |
| 321.38 | 3.37 | 3.37 |
| 237.21 | 1.87 | 1.87 |
| 251.24 | 2.26 | 2.26 |
| 220.27 | 3.23 | 3.23 |
| 371.44 | 4.53 | 4.53 |
| 397.48 | 5.04 | 5.04 |
| 150.14 | 1.33 | 1.33 |
| 375.43 | 3.48 | 3.48 |
| 407.91 | 4.60 | 4.60 |