Basic Information
ID: ALA4736773
Type: Binding
Description: Binding affinity to FKBP12 (unknown origin) expressed in HEK293 cells co-expressing FRB assessed as inhibition of rapamycin-induced FKBP12-FRB dimerization at 3 mM measured after 25 mins by nano-glo live cell reagent based luminescence assay relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4736773
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 369.45 | 3.45 | 3.45 |
| 454.98 | 4.54 | 4.54 |
| 307.38 | 2.40 | 2.40 |
| 283.74 | 2.31 | 2.31 |
| 423.42 | 4.16 | 4.16 |
| 407.42 | 4.46 | 4.46 |
| 321.25 | 2.21 | 2.21 |
| 277.35 | 2.01 | 2.01 |
| 279.32 | 1.66 | 1.66 |
| 335.43 | 3.25 | 3.25 |
| 423.42 | 4.16 | 4.16 |
| 369.45 | 3.45 | 3.45 |
| 249.29 | 1.66 | 1.66 |
| 321.40 | 3.00 | 3.00 |
| 321.40 | 3.00 | 3.00 |
| 279.32 | 1.66 | 1.66 |
| 335.43 | 3.25 | 3.25 |