Basic Information
ID: ALA4736777
Type: Binding
Description: Stabilization of FKBP12/RyR1 protein-protein interaction in human 8220 myoblast-derived myotubes assessed as reversal of SIN1-induced intracellular calcium leakage at 150 nM preincubated for 12 hrs followed by SIN1 stimulation and measured after 6 hrs by fura-2 AM dye based fluorescence assay relative to control
Organism: Homo sapiens
Cell type: Myotube
Activity Charts
Bioactivity
Activity Types for Assay ALA4736777
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 209.31 | 2.23 | 2.23 |
| 369.45 | 3.45 | 3.45 |
| 454.98 | 4.54 | 4.54 |
| 307.38 | 2.40 | 2.40 |
| 283.74 | 2.31 | 2.31 |
| 423.42 | 4.16 | 4.16 |
| 407.42 | 4.46 | 4.46 |
| 321.25 | 2.21 | 2.21 |
| 277.35 | 2.01 | 2.01 |
| 279.32 | 1.66 | 1.66 |
| 423.42 | 4.16 | 4.16 |
| 369.45 | 3.45 | 3.45 |
| 249.29 | 1.66 | 1.66 |
| 321.40 | 3.00 | 3.00 |
| 279.32 | 1.66 | 1.66 |
| 335.43 | 3.25 | 3.25 |