Basic Information
ID: ALA4737248
Type: Binding
Description: Agonist activity at recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in intra cellular calcium level after 10 mins by fluorescence relative to control
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA4737248
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.90 | 3.93 | 3.93 |
| 388.88 | 3.96 | 3.96 |
| 402.90 | 4.35 | 4.35 |
| 373.41 | 2.92 | 2.92 |
| 437.35 | 5.00 | 5.00 |
| 404.88 | 3.62 | 3.62 |
| 415.90 | 3.82 | 3.82 |
| 388.88 | 4.04 | 4.04 |
| 389.86 | 3.43 | 3.43 |
| 442.93 | 2.93 | 2.93 |
| 418.90 | 3.93 | 3.93 |
| 452.87 | 2.93 | 2.93 |
| 419.89 | 3.20 | 3.20 |
| 388.88 | 4.24 | 4.24 |
| 398.48 | 3.70 | 3.70 |
| 372.42 | 3.52 | 3.52 |
| 429.93 | 4.21 | 4.21 |
| 386.45 | 3.83 | 3.83 |
| 382.49 | 4.00 | 4.00 |
| 424.40 | 3.19 | 3.19 |
| 423.42 | 3.80 | 3.80 |
| 403.89 | 3.82 | 3.82 |
| 402.90 | 4.35 | 4.35 |
| 389.86 | 3.43 | 3.43 |
| 402.45 | 3.42 | 3.42 |
| 386.45 | 3.74 | 3.74 |
| 372.42 | 3.73 | 3.73 |
| 405.86 | 3.02 | 3.02 |
| 389.86 | 3.43 | 3.43 |
| 430.92 | 3.08 | 3.08 |
| 403.44 | 2.69 | 2.69 |
| 402.90 | 4.35 | 4.35 |
| 389.41 | 2.50 | 2.50 |
| 385.45 | 2.79 | 2.79 |
| 388.42 | 3.11 | 3.11 |
| 375.84 | 3.04 | 3.04 |
| 368.46 | 3.69 | 3.69 |
| 466.90 | 3.32 | 3.32 |
| 414.48 | 3.29 | 3.29 |
| 418.90 | 3.93 | 3.93 |