Assay Report Card

Basic Information

ID: ALA4737249

Type: Binding

Description: Positive allosteric modulation of recombinant human nAChRalpha7 expressed in HEK293 Flip-In cells co-expressing RIC3 assessed as increase in choline-induced inward current at 10 uM after 6 to 10 mins by whole-cell patch clamp method

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
402.904.354.35
442.932.932.93
389.863.433.43